Avinash Sachdev as Dev Raj Purohit (Male Protagonist),
Rubina Dilaik as Radhika/Ruby Bhardwaj (Female Protagonist),
Gopi Desai as Dai Maa,
Benaf Dadachandji as Barkha (Female antagonist,),
Saurav Chakraborty as Rohan Harinath Purohit Antagonist),
Micckie Dudaaney as Virat Gopaldas Purohit,
Sushmita Daan as Padma Harinath Purohit,
Rakesh Pandey as Dadaji,
Sangeeta Kapure as Mohini Virat Purohit,
Chayan Trivedi as Gopaldas Purohit,
Aditya Lakhia as Mansaram.
Sidharth Sen as Chhenu,
Nishant Shokeen/Pracheen Chauhan as Kanha (Lord Krishna),
Aman Verma as Asur/Vishwanat (Antagonist ),
Vinay Jain as Rishikesh Bhardwaj (RB),
Kishwar Merchant as Sonia Bhardwaj,
Srishty Rode as Radha Rani/Madhvi.
Chotti Bahu is the love saga of two soul mates Dev and Radhika.
Radhika (Rubina Dilaik) was adopted and brought up by a family of weavers in a small town called Rawal. Dev (Avinash Sachdev) visits Rawal as a child on the occasion of Radhashtami. Dev and Radhika meet each other and become good friends. Radhika and Dev's families tie them in the bond of marriage in their tender age.